一條片簡單解釋mRNA疫苗導致心肌炎腎炎原理

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460 Like 95 Dislike
2021-08-22 16:34:16
打針有分im iv
今次支針打肌肉 佢打左落靜脈會引起副作用
打大腿應該係冇咁易打錯血管同埋都離心臟遠d
2021-08-22 16:34:30
想問下其實心肌同心包炎會唔會好得番疫苗會唔會搞到佢又再發炎?定係一次就無架
2021-08-22 16:34:50
絲打咁有時間同佢慢慢玩嘅
見你同佢已經玩左幾頁
2021-08-22 16:35:40
打大腿咪容易有賓周炎囉
2021-08-22 16:36:12
要用自己細胞整出spike protein去扮帶有spike protein嘅covid virus trigger immune response其實真係有d擔心唔擔心就假
2021-08-22 16:36:19
其實兒登咁多教授/學者點解未出自已疫苗
2021-08-22 16:37:36
岩,所以我咪話我中左賓周炎,有粒muscle cell痾尿果陣經過賓周
2021-08-22 16:38:59
點解你粒muscle cell黎自你條賓周
賓周size -1
2021-08-22 16:39:41
真心一問知唔知點report post
極懷疑條友扮醫療,散播謠言
2021-08-22 16:39:56
人體circulation好撚神奇嫁,我賓周size+10
2021-08-22 16:42:42
你homeobox有問題
2021-08-22 16:44:58
咁你痾尿會唔會痾左個腦出黎
2021-08-22 16:46:45
見你呢個算係最認真嘅comment我答多次

Virus嘅genomic materials 係除咗spike protein 仲有佢成個身嘅其他proteins. 佢地用你個細胞製造完就會resemble番個virus, 再走出個infected cell and then 去infect other cells. Virus 入細胞係require different parts on the capsule not the spike protein only.

mRNA vaccine唔同. 佢淨係encode左spike protein. 無入nucleus 所以個肌肉細胞死你個身體就少左啲細胞係express spike protein. 係肌肉細胞製造嘅spike protein大部份淨係會express 喺番that particular muscle cell嘅表面. 唔排除有啲會經exocytosis咁經exosomes secrete 走. 但係入到其他細胞都係lysosome 整爛晒, 唔會係其他細胞表面express. 一粒protein係唔會itself咁係個細胞到噴咗出嚟然後走去第二個位accumulate

mRNA唔stable 唔代表你打多啲就work. 成件事係要配合返有lipid nano particle (LNP). 要靠LNP先可以經endocytosis入細胞, 個lipid provide an appropriate charge比條mRNA可以做到lysosomal escape, 然後先function 到. 所以mRNA自己本身係入唔到你身體其他細胞做成影響.

俾返個Credit你, 其實一條mRNA可以製造幾多protein係長遠黎講如果我哋想expand 個technology 去做治療(vaccine唔算治療)係我地科學家要好嚴謹去解答嘅問題. 例如如果我哋想打啲encoded growth hormone嘅藥, 我地唔會想over express. 但係而家vaccine係only need to trigger adequate immune response. 個數唔洗好嚴謹. (當然我講嘅唔嚴謹唔代表求L其)
2021-08-22 16:46:52
你個腦起spike surface area又多左係咪又聰明左
2021-08-22 16:49:46
一個係APC 一個係潛伏喺細胞入邊。點比呀大佬
呢個只係好基本嘅immune reaponse 你可唔可以再進修過幾年先返去做醫護
2021-08-22 16:50:37
2021-08-22 16:51:12
唔會有人理你架喇傻仔
一係你心理作用
一係你敏感體質
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