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1,3-BPG can be converted into 2,3-BPG, which promotes the release of oxygen from hemoglobin.
When blood oxygen level is low, the body will produce more 1,3-BPG, which will be converted into 2,3-BPG so as to release more oxygen from hemoglobin to ensure sufficient oxygen supply to body cells.
Therefore, a high 1,3-BPG level (as well as a higher 2,3-BPG level) indicates a low blood oxygen level.