智利研究:一劑科興毫無保護力

162 回覆
166 Like 2 Dislike
2021-04-08 10:36:52
咁你唔搵返Nature條link出嚟?
2021-04-08 10:38:36
你個link 話輝瑞對南非變種失效9-14倍窩。。你有無睇架??
2021-04-08 10:38:58
貼左啦
2021-04-08 10:40:04
你枝科興直頭冇數據添
仲喺度鳩噏mRNA vaccine對南非種失效四五十倍
2021-04-08 10:46:24
As compared with the D614G variant, we found that B.1.429 was approximately 2 to 3 times less sensitive to neutralization by convalescent serum and by serum samples obtained from vaccinated persons, whereas B.1.351 was approximately 9 to 14 times less sensitive to neutralization
9 至14倍 窩, 你有無睇架,你仲貼出黎俾唔睇?
2021-04-08 10:47:08
係有數據,科興對南非變種失效1.6 倍。
2021-04-08 10:49:09
你個link 話就話9 -14 倍,但係用假病毒仲要係得20個sample.
人地有90 個真南非變種病毒sample, 得出結果係失效40倍。
2021-04-08 10:49:34
其實搵唔搵到香港每日猝死/突發心血管病發死嘅數據(by age),我真係好想知有幾common
2021-04-08 10:54:23
https://www.biorxiv.org/content/10.1101/2021.02.01.429069v1.full

科興對南非變種失效1.6倍

輝瑞同莫德納對南非變種失效最高40倍!!
2021-04-08 10:58:41
paper呢?

而家睇到嘅data係
就算convalescent plasma對B.1.351
都低antibody response
甚至低到近乎零

但問題係
你一味講fold decrease
如果一開始枝針對wild type嘅neutralisation都唔係高
對B.1.351 mutant嘅話
佢嘅neutralisation efficacy當然會跌得冇咁多

10分跌去1分 就係-10 fold
2分跌去1分 就係-2 fold
所以科興咪冇乜失效囉
由一開始都冇乜效
點跌都唔會跌得多
2021-04-08 11:00:09
2021-04-08 11:00:24
BioRXiv
又一間冇Peer review嘅
喂你睇下個名啦
BioRXiv同MedRXiv係兩兄弟嚟架
2021-04-08 11:02:46
BBIBP-CorV同RBD ZF2001開你科興撚事?
2021-04-08 11:03:21
咁唔算數據黎,你貼嘅邊個link 係話有peer reviewed??
2021-04-08 11:03:55
條友出撚晒名五毛黎,巴打你都係慳返啖氣好過
2021-04-08 11:04:31
咁點解條數都係高
係咪間接證明隻疫苗冇乜用
2021-04-08 11:04:56
Nature Medicine就不嬲都係Peer review
NEJM都係
你自己睇下人地嘅impact大幾多先啦
坐勞改營就唔使學嘢咩二毛
2021-04-08 11:05:36
我覺得勞改營應該出糧畀我
我而家教埋佢點樣睇paper
2021-04-08 11:05:51
BBIBP-CorV 咪即係科興囉。。
2021-04-08 11:06:51
係俾peer review, 唔係peer reviewed.
無返3 5 7 個月點會reviewed 呀?
2021-04-08 11:07:57
一劑無保護力咪打夠一百枝
2021-04-08 11:07:57
你勞改到懵撚咗?
SinoPharm同SinoVac唔撚識分
屌叫你老頂出嚟啦
做二毛做到你咁點減刑呀
2021-04-08 11:08:27
給我打 往死裏打
2021-04-08 11:08:50
你自己貼個link 話輝瑞對南非變種失效9-14倍。
就當原本95%, 失效14倍係咪即係變0 %?
D 數太難唔識計添~
2021-04-08 11:09:49
岩岩check左英國政府講AZ既問題:

https://www.gov.uk/government/news/mhra-issues-new-advice-concluding-a-possible-link-between-covid-19-vaccine-astrazeneca-and-extremely-rare-unlikely-to-occur-blood-clots

- 44 of the 79 cases were of CVST with thrombocytopenia
- 35 of the 79 cases were of thrombosis in other major veins with thrombocytopenia

https://en.wikipedia.org/wiki/Heparin-induced_thrombocytopenia
岩岩睇左呢隻由肝素導致既低血小板病, 會令到血小板形成血栓, 成因係打呢隻肝素入身體會有極細機率生成抗體攻擊肝素, 減低抗凝血能力而形成血栓

EMA果邊report左呢個可能性
https://www.ema.europa.eu/en/news/astrazenecas-covid-19-vaccine-ema-finds-possible-link-very-rare-cases-unusual-blood-clots-low-blood

即係打針前要check凝血指數, 如果發現凝血能力有問題就會有更大機率出現血栓
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