點解唐氏綜合症個d人個個一樣樣

164 回覆
15 Like 81 Dislike
2017-03-26 05:10:42
痴線,咁多人識少少就不斷趁機拋書包話因為多左條染色體,一係就一句病徵就當答左,全部都答唔對題。
唔識答就收聲啦

假設多出黎果條chromosome係有A, B, C gene
每個有down syndrome既人都會多左A,B,C gene
咁每個人多左出黎既野都係一樣,所以個樣就會好似

唔係咁簡單

1. 重點在於difference in genes in coding region among all "extra 21st chromosome"

2. 每一位Down syndrome 病人既extra 21st chromosome 一定來自爸爸/媽媽一方
-> 但每一個人既genes in coding region for phenotypic expression 根本唔同,not to mention the extra 21st chromosome(more accurately the extra chromatin since protein synthesis takes place before the duplication of chromosomes)
-> 所以你既推論話各自多A B C唔係完全正確,因為 A B C phenotype 既gene differences vary from ppl to ppl

利申:17dse

事實上其實佢地樣貌有分別,但「分別程度」未必我地正常人可以觀察到

但點解有common features(phenotypic expression):
我估計「可能,只係可能」,根本人體21st a pair of homologous chromosome上,differences in genes in coding region among all individuals 分別唔大gwa

Gene coding region就算喺唔同individuals都係conserved
個code會可能有啲唔同,但個sequence同個位置基本上係conserved,稱為consensus sequence
某啲gene嘅sequence of coding regions直頭係conserved across species
所以down syndrome patient個樣會似係因為佢地出事嘅係同一條chromosome,咁啱係控制緊同一樣野

點解我地會分唔到就係好似條reddit link入面咁講
我地係唔擅於分辨唔係自己族/常見嘅人嘅樣
好似白人覺得亞洲人一樣樣,我地覺得佢地又係一樣樣咁
如果你細睇係會睇得出down syndrome patient佢地個樣唔同
但平時冇咩接觸嘅情況下,你每見一過都只會記得佢大概嘅面部輪廓
到你見到下一個嘅時候用腦入面嘅印象嚟對比就自然會覺得佢地係一樣樣
因為你只係留意到佢地嘅大致輪廓


thanks bro
但照計即使係conserved region也好, sequence among individuals都會唔同(呢樣野解釋到即使相同conserved region for a specific characteristics(phenotypic expression), 但容許有different traits of a character

所以我有一點唔明在於,即使down syndrome patient 出事全部在於extra 21 chromosome, 但每一條distinct chromosome 上既sequence都唔同,即使控制同一樣都好,都會好'唔同expression'

但點解你話因為咁岩,所以'好似'?


應該咁講
就算係different traits都好
如果某啲mutation嘅phenotypic effect夠大的話
Trait difference係可以變到insignificant
假設某啲人個鼻尖到人中有2cm,稱為高鼻
某啲人個鼻尖到人中得1cm,稱為扁鼻
如果有某樣genetic mutation可以大幅度㩒低鼻嘅高度嘅
當兩面都咁上下扁嘅時候
望落去就會好似冇分別咁

之後就係呢個post一路有人講嗰樣野
就係我地唔擅長分辨唔係自己種族/唔常見到嘅人
2017-03-26 05:21:37
痴線,咁多人識少少就不斷趁機拋書包話因為多左條染色體,一係就一句病徵就當答左,全部都答唔對題。
唔識答就收聲啦

假設多出黎果條chromosome係有A, B, C gene
每個有down syndrome既人都會多左A,B,C gene
咁每個人多左出黎既野都係一樣,所以個樣就會好似

唔係咁簡單

1. 重點在於difference in genes in coding region among all "extra 21st chromosome"

2. 每一位Down syndrome 病人既extra 21st chromosome 一定來自爸爸/媽媽一方
-> 但每一個人既genes in coding region for phenotypic expression 根本唔同,not to mention the extra 21st chromosome(more accurately the extra chromatin since protein synthesis takes place before the duplication of chromosomes)
-> 所以你既推論話各自多A B C唔係完全正確,因為 A B C phenotype 既gene differences vary from ppl to ppl

利申:17dse

事實上其實佢地樣貌有分別,但「分別程度」未必我地正常人可以觀察到

但點解有common features(phenotypic expression):
我估計「可能,只係可能」,根本人體21st a pair of homologous chromosome上,differences in genes in coding region among all individuals 分別唔大gwa

Gene coding region就算喺唔同individuals都係conserved
個code會可能有啲唔同,但個sequence同個位置基本上係conserved,稱為consensus sequence
某啲gene嘅sequence of coding regions直頭係conserved across species
所以down syndrome patient個樣會似係因為佢地出事嘅係同一條chromosome,咁啱係控制緊同一樣野

點解我地會分唔到就係好似條reddit link入面咁講
我地係唔擅於分辨唔係自己族/常見嘅人嘅樣
好似白人覺得亞洲人一樣樣,我地覺得佢地又係一樣樣咁
如果你細睇係會睇得出down syndrome patient佢地個樣唔同
但平時冇咩接觸嘅情況下,你每見一過都只會記得佢大概嘅面部輪廓
到你見到下一個嘅時候用腦入面嘅印象嚟對比就自然會覺得佢地係一樣樣
因為你只係留意到佢地嘅大致輪廓


thanks bro
但照計即使係conserved region也好, sequence among individuals都會唔同(呢樣野解釋到即使相同conserved region for a specific characteristics(phenotypic expression), 但容許有different traits of a character

所以我有一點唔明在於,即使down syndrome patient 出事全部在於extra 21 chromosome, 但每一條distinct chromosome 上既sequence都唔同,即使控制同一樣都好,都會好'唔同expression'

但點解你話因為咁岩,所以'好似'?


應該咁講
就算係different traits都好
如果某啲mutation嘅phenotypic effect夠大的話
Trait difference係可以變到insignificant
假設某啲人個鼻尖到人中有2cm,稱為高鼻
某啲人個鼻尖到人中得1cm,稱為扁鼻
如果有某樣genetic mutation可以大幅度㩒低鼻嘅高度嘅
當兩面都咁上下扁嘅時候
望落去就會好似冇分別咁

之後就係呢個post一路有人講嗰樣野
就係我地唔擅長分辨唔係自己種族/唔常見到嘅人

全部都理解

惟一想知,咁個mutation effect is what?
2017-03-26 05:26:36

假設多出黎果條chromosome係有A, B, C gene
每個有down syndrome既人都會多左A,B,C gene
咁每個人多左出黎既野都係一樣,所以個樣就會好似

唔係咁簡單

1. 重點在於difference in genes in coding region among all "extra 21st chromosome"

2. 每一位Down syndrome 病人既extra 21st chromosome 一定來自爸爸/媽媽一方
-> 但每一個人既genes in coding region for phenotypic expression 根本唔同,not to mention the extra 21st chromosome(more accurately the extra chromatin since protein synthesis takes place before the duplication of chromosomes)
-> 所以你既推論話各自多A B C唔係完全正確,因為 A B C phenotype 既gene differences vary from ppl to ppl

利申:17dse

事實上其實佢地樣貌有分別,但「分別程度」未必我地正常人可以觀察到

但點解有common features(phenotypic expression):
我估計「可能,只係可能」,根本人體21st a pair of homologous chromosome上,differences in genes in coding region among all individuals 分別唔大gwa

Gene coding region就算喺唔同individuals都係conserved
個code會可能有啲唔同,但個sequence同個位置基本上係conserved,稱為consensus sequence
某啲gene嘅sequence of coding regions直頭係conserved across species
所以down syndrome patient個樣會似係因為佢地出事嘅係同一條chromosome,咁啱係控制緊同一樣野

點解我地會分唔到就係好似條reddit link入面咁講
我地係唔擅於分辨唔係自己族/常見嘅人嘅樣
好似白人覺得亞洲人一樣樣,我地覺得佢地又係一樣樣咁
如果你細睇係會睇得出down syndrome patient佢地個樣唔同
但平時冇咩接觸嘅情況下,你每見一過都只會記得佢大概嘅面部輪廓
到你見到下一個嘅時候用腦入面嘅印象嚟對比就自然會覺得佢地係一樣樣
因為你只係留意到佢地嘅大致輪廓


thanks bro
但照計即使係conserved region也好, sequence among individuals都會唔同(呢樣野解釋到即使相同conserved region for a specific characteristics(phenotypic expression), 但容許有different traits of a character

所以我有一點唔明在於,即使down syndrome patient 出事全部在於extra 21 chromosome, 但每一條distinct chromosome 上既sequence都唔同,即使控制同一樣都好,都會好'唔同expression'

但點解你話因為咁岩,所以'好似'?


應該咁講
就算係different traits都好
如果某啲mutation嘅phenotypic effect夠大的話
Trait difference係可以變到insignificant
假設某啲人個鼻尖到人中有2cm,稱為高鼻
某啲人個鼻尖到人中得1cm,稱為扁鼻
如果有某樣genetic mutation可以大幅度㩒低鼻嘅高度嘅
當兩面都咁上下扁嘅時候
望落去就會好似冇分別咁

之後就係呢個post一路有人講嗰樣野
就係我地唔擅長分辨唔係自己種族/唔常見到嘅人

全部都理解

惟一想知,咁個mutation effect is what?

你係指trisomy 21嘅effect?
定係指我話扁鼻個effect?
前者wiki應該有
後者係我鳩噏
2017-03-26 05:34:48

唔係咁簡單

1. 重點在於difference in genes in coding region among all "extra 21st chromosome"

2. 每一位Down syndrome 病人既extra 21st chromosome 一定來自爸爸/媽媽一方
-> 但每一個人既genes in coding region for phenotypic expression 根本唔同,not to mention the extra 21st chromosome(more accurately the extra chromatin since protein synthesis takes place before the duplication of chromosomes)
-> 所以你既推論話各自多A B C唔係完全正確,因為 A B C phenotype 既gene differences vary from ppl to ppl

利申:17dse

事實上其實佢地樣貌有分別,但「分別程度」未必我地正常人可以觀察到

但點解有common features(phenotypic expression):
我估計「可能,只係可能」,根本人體21st a pair of homologous chromosome上,differences in genes in coding region among all individuals 分別唔大gwa

Gene coding region就算喺唔同individuals都係conserved
個code會可能有啲唔同,但個sequence同個位置基本上係conserved,稱為consensus sequence
某啲gene嘅sequence of coding regions直頭係conserved across species
所以down syndrome patient個樣會似係因為佢地出事嘅係同一條chromosome,咁啱係控制緊同一樣野

點解我地會分唔到就係好似條reddit link入面咁講
我地係唔擅於分辨唔係自己族/常見嘅人嘅樣
好似白人覺得亞洲人一樣樣,我地覺得佢地又係一樣樣咁
如果你細睇係會睇得出down syndrome patient佢地個樣唔同
但平時冇咩接觸嘅情況下,你每見一過都只會記得佢大概嘅面部輪廓
到你見到下一個嘅時候用腦入面嘅印象嚟對比就自然會覺得佢地係一樣樣
因為你只係留意到佢地嘅大致輪廓


thanks bro
但照計即使係conserved region也好, sequence among individuals都會唔同(呢樣野解釋到即使相同conserved region for a specific characteristics(phenotypic expression), 但容許有different traits of a character

所以我有一點唔明在於,即使down syndrome patient 出事全部在於extra 21 chromosome, 但每一條distinct chromosome 上既sequence都唔同,即使控制同一樣都好,都會好'唔同expression'

但點解你話因為咁岩,所以'好似'?


應該咁講
就算係different traits都好
如果某啲mutation嘅phenotypic effect夠大的話
Trait difference係可以變到insignificant
假設某啲人個鼻尖到人中有2cm,稱為高鼻
某啲人個鼻尖到人中得1cm,稱為扁鼻
如果有某樣genetic mutation可以大幅度㩒低鼻嘅高度嘅
當兩面都咁上下扁嘅時候
望落去就會好似冇分別咁

之後就係呢個post一路有人講嗰樣野
就係我地唔擅長分辨唔係自己種族/唔常見到嘅人

全部都理解

惟一想知,咁個mutation effect is what?

你係指trisomy 21嘅effect?
定係指我話扁鼻個effect?
前者wiki應該有
後者係我鳩噏

Oic so sad😂😂

我覺得如果唔同base sequences in a distinct extra 21 chromosome
-> 點都會唔同
-> 但唔同既程度我地睇唔睇得出先係問題😂😂
-> 至於點解有similar trisomy effect, 就唔係我能力範圍了,所以算數,繼續溫ls😭
2017-03-26 09:52:25
女人過四十歲以上產子
胎兒患上唐氏綜合症既機會率就會高過常人好多倍
2017-03-26 10:25:37
女人過四十歲以上產子
胎兒患上唐氏綜合症既機會率就會高過常人好多倍

其實36歲開始個危險性係近乎exponential咁升
所以好多人都話有仔趁嫩生
2017-03-26 11:40:39
其實依家唔係未生就check 到嫁咩?
點解仲會有人肯生出黎受苦

除非真係有錢 如果家境一般都唔應該生特殊小朋友出嚟
嗰啲treatment成幾廿萬幾百萬
2017-03-26 11:42:41
女人過四十歲以上產子
胎兒患上唐氏綜合症既機會率就會高過常人好多倍

其實36歲開始個危險性係近乎exponential咁升
所以好多人都話有仔趁嫩生

過左過咗40定係45唔記得 去到最後差唔多10%
2017-03-26 13:53:52


每隔一排就有人問 當年今日

依d先叫做答案
上邊個個講病徵做乜鳩
病徵都算係答案?

樓上咪講咗點解囉
但好懷疑你地明唔明姐
2017-03-26 14:11:12
深入淺出既講法一睇就明

我個frd 叫果d 做一樣樣病
我稱佢地做唐記

非歧視
2017-03-26 15:24:31
深入淺出既講法一睇就明

我個frd 叫果d 做一樣樣病
我稱佢地做唐記

非歧視

唐記包點
2017-03-26 15:31:06
深入淺出既講法一睇就明

我個frd 叫果d 做一樣樣病
我稱佢地做唐記

非歧視

唐記包點

我成日食唐記
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