玩DNA?
之前五毛復興條柒頭先玩完
而家又loop?
Source: Chen, J., Zheng, H., Bei, J.-X., Sun, L., Jia, W., Li, T., … Liu, J. (2009). Genetic Structure of the Han Chinese Population Revealed by Genome-wide SNP Variation. American Journal of Human Genetics, 85(6), 775–785.
http://doi.org/10.1016/j.ajhg.2009.10.016
Figure 1: Population Stratification of the Han Chinese
The PCA plots were oriented with PC1 on the y axis and with PC2 on the x axis. These plots were obtained by using all 107,565 SNPs.
(A) The cluster and stratification of the samples from the ten provinces of China, showing an evident north-south genetic differentiation.
(B) The samples from Beijing (purple) (CHB samples from the International HapMap project), Shanghai (orange), and Singapore (yellow) were compared against the provincial samples. The majority of the Singapore samples fall in the southern (lower) sector, whereas the Beijing and Shanghai samples were largely located within the northern (upper) sector.
(C) The three dialect groups from the Guangdong province were shown against all of the Han Chinese samples from the ten provinces. There was stratification among the three dialect groups, along the same north-south trend observed for the overall Han Chinese.
Figure 1嘅3個panels (A, B, C)已經睇到廣東人嘅基因組成同北方漢人唔同
而且相當集中返喺廣東 唔係好喺其他地方搵到
Figure 2: Comparison between the Geographic Map of China and the Genetic Structure of the Han Chinese
The PCA plots of the provincial samples are superimposed on the map of China to show the general north-south trend across China.
Figure 2 直頭畫埋你睇廣東人嘅基因結構同廣東以北嘅漢人基因結構係明顯唔同
Figure 3: Estimated Population Structure by STRUCTURE for K = 2 and K = 3
Each individual is represented by a thin vertical line, and each province is demarcated by a thick vertical black line. The provinces are arranged from north to south, with JPT on the extreme left, representing the northernmost locality, to Liaoning, the northernmost province of China investigated in this study. The Guangdong individuals were grouped into the three dialect groups of Teochew, Hakka and Cantonese. These were then followed by the samples from the two metropolitan cities of Beijing (represented by CHB) and Shanghai, as well as the overseas Chinese community in Singapore. In K = 2, the northern provinces are clearly anchored by the JPT, with a huge membership of northern samples (represented by the yellow segment). The northern membership decreases gradually down to the southern provinces, which show a strong membership of southern samples (represented by the brown segment). At K = 3, JPT is clearly separated from the Han Chinese samples. The analysis revealed a demarcation of north-central-south similar to that shown by Figure 2. The Beijing, Shanghai and Singapore samples showed a clear mixture of southern (long brown lines) and northern (shorter brown lines) individuals, as compared to the provincial samples. The three dialect samples from the Guangdong province were also different from each other, with Teochew being more similar to individuals from the provinces of Hunan and Cantonese being the most southern representative.
CHB係北京人
Figure 3 一睇已經睇到廣東人同北方漢人嘅基因有幾大分別
有趣嘅係日本人(JPT)同北方漢人喺基因上係幾接近
漢你碌撚