But with the Committee now allowing everyone above 45 years age to be unblinded, the trial can continue only in those below that age bar. “
A significant number of participants will no longer be available to study the vaccine efficacy once unblinding of participants above 45 years is carried out,” says Dr. Anant Bhan, global health and bioethics researcher based in Bhopal. “With the current surge in cases, more younger people are getting infected.” In all likelihood, the phase 3 trial may achieve its final endpoint of 130 cases but the trial will not include the most vulnerable population of participants above 45 years.
https://www.google.com.hk/amp/s/www.thehindu.com/sci-tech/health/sec-allows-bharat-biotech-to-unblind-all-participants-above-45-years/article34214933.ece/amp/
嚴重打擊
睇Reddit啲人討論
45歲以上嘅人unblinded to the study
我唔知具體即係咩意思
但應該會影響45歲以上人士數據收集
可能會令phase 3 result 仲有排等
冇呢個數據唔會得到FDA approval