There are no significant issues when using the LG 40WP95C with a recent MacBook Pro. The variable refresh rate feature doesn't work, but sleep mode works properly, and everything returns to its original position when your wake your computer up. The 96W of power delivery is enough to keep most MacBooks fully charged, but some of the larger MacBook Pros require 140W, so this won't be enough to keep them fully charged if they're running under heavy load.