https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciac142/6530400?searchresult=1
Vaccination protected testicular damage after SARS-CoV-2 challenge
Hamsters immunized with two doses of intramuscular inactivated whole virion vaccine 14 days apart [14] were intranasally challenged with 103 PFU of SARS-CoV-2 HK-13 14 days after second vaccination. Testes were examined at 4 and 28dpi (Figure 10A). Serum neutralizing antibodies were detected from all vaccinated animals after challenge at 4dpi and 28dpi, with GMT of 160±43.82 and 120±23.09, respectively. Testicles showed no histopathological changes in all nine vaccinated hamsters (Figure 10B). One group of hamsters (n=7) were challenged with 103 PFU at 3 days after first vaccination showed no testicular histopathological damage at 4dpi (Figure 10B), indicating that vaccination effectively protects testes from SARS-CoV-2 infection.