日本研究：確認新抑鬱及焦慮症致病機制，服用薑黃素可改善抑鬱焦慮行為！

??tate

薑黃粉提煉後先得2-6%
可想而知粉有幾多薑黃素
代謝又快 身體未用到已經無左

此人係你呀媽 = 此人係女人
相反黎講，即係 此人唔係你呀媽 = 此人不是女人

死咗老婆係咪唔知足？

COVID如果個根源解決到=唔再有COVID
咁即係COVID as a disease 唔存在

根源解決=有效疫苗/任何可以滅絕covid嘅方法=covid就算存在都無影響

而covid係由virus引起，有憑據
而後天depression患者無中生有，呢20年病患人數離奇急升

Depression由根源引起，有憑據

哦

唔怪得啲電影咁能stone

抑鬱始終involve到大腦太複雜，好難格硬同一個理由去總結
以下係科學界主流認同嘅致抑鬱成因
https://www.health.harvard.edu/depression/how-genes-and-life-events-affect-mood-and-depression

抑鬱同時都係講緊大腦構造同運作嘅問題
補充埋呢度有個研究發現有抑鬱嘅女人嘅hippocampus係細過冇抑鬱嘅女人大約9%至13%

Research shows that the hippocampus is smaller in some depressed people. For example, in one fMRI study published in The Journal of Neuroscience, investigators studied 24 women who had a history of depression. On average, the hippocampus was 9% to 13% smaller in depressed women compared with those who were not depressed.

好多人成日提到嘅化學物質失衡理論反而仲有好多疑問

[url]Researchers are exploring possible links between sluggish production of new neurons in the hippocampus and low moods. An interesting fact about antidepressants supports this theory. These medications immediately boost the concentration of chemical messengers in the brain (neurotransmitters). Yet people typically don't begin to feel better for several weeks or longer. Experts have long wondered why, if depression were primarily the result of low levels of neurotransmitters, people don't feel better as soon as levels of neurotransmitters increase.[/url]


https://www.health.harvard.edu/mind-and-mood/what-causes-depression

再補充埋
雖然未有直接證據，但係專家相信壓力會抑制hippocampus製造new neurons (nerve cells)，所以佢哋認為壓力好有可能就係造成hippocampus縮細嘅原因
亦即係話唔一定係天生，後天都可以影響大腦結構

唔係好明 人天生應該唔係有強大意志 咁無強大意志有咩問題

咩叫“人天生應該唔係有強大意志”？

字面咁解 強大意志未必係與生俱來

why not
你嘅祖先為咗生你落黎，學打獵，避巨獸，生火瀘水，點解生完你落黎會突然無咗強大意志，你有無静心諗過。

其實係相反，個個人生落黎都有“我要生存落去”嘅dna，只係因為呢一刻世界太和平太舒服，所以養成咗一堆無意志力嘅人。

時代唔同左 個社會要面對嘅問題都唔同左

哦哦
因為時代唔同左 個社會要面對嘅問題都唔同左
所以大家唔再需要有意志力

good point

唔係唔需要 我以為我哋唔係討論緊有冇需要有意志力

而係客觀地睇而家呢個時代係咪有抑鬱症呢樣嘢 我以為事實上係存在

強大意志係你個人嘅assumption，你以為以前冇係因為以前根本冇呢個framework同知識去做diagnosis
下面個study用NHP model，NHP即係Nonhuman primate咁解
They are especially appropriate for studying developmental variables, as many aspects of NHP infancy and social functioning are similar to humans, whereas development occurs at an accelerated rate allowing for more rapid assessment of experimental variables.

入面嘅採樣、觀察同埋實驗過程太長太detailed我唔會幫你做總結
有心自己啪晒佢先再落定論，唔該

It is interesting to note that some adult wild-born macaques spontaneously exhibit depressive behaviors even though they have not been subjected to experimentally induced early-life stress (Camus et al. 2014; Shively et al. 1997; Willard and Shively 2012).

NHP studies show that experiences during development interact with underlying genetic and/or other physiologic profiles to alter known (and undoubtedly many unknown) aspects of the CNS, thereby predisposing individuals to depression later in life. This takes depression out of the realm of an emotional state and into the realm of organic disease, much like diabetes or cancer, whereby underlying predispositions are acted on by the environment to produce pathology.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240441/

等我開番間藥廠，賣抑鬱藥，請你做marketing 一定好好搵

唔同你，我至少會去搵資料，學識antidepressants呢樣嘢唔係百發百中，事實上有效率根本冇大眾諗咁高
你呢啲我覺得我認為嘅assumption完全反映到你份人有幾不學無術

Without antidepressants: About 20 to 40 out of 100 people who took a placebo noticed an improvement in their symptoms within six to eight weeks.
With antidepressants: About 40 to 60 out of 100 people who took an antidepressant noticed an improvement in their symptoms within six to eight weeks.

antidepressants improved symptoms in about an extra 20 out of 100 people

https://www.ncbi.nlm.nih.gov/books/NBK361016/

效率唔重要，賣藥啫，你水多d人買咪得我理得佢有唔有效 隻病本來就唔存在嫁啦

宜家d藥廠都係咁諗 所以先會說服你地有呢種病存在啫



真係好好笑其實 如果係減肥藥 100個人得20個人食完輕左少少 你哋一定會話呃錢 一定會話係scam

但一講到抑鬱 你班人就好似邪教上身咁周圍同人講呢種“病”存在

一隻病，以前無，呢15年突然患者暴增。
病嘅成因唔清楚。
點解會患上唔清楚，幾百套理論。
呢種病唔清楚成因但係又唔知點解有藥食。
但係食完藥唔擔保有效。
100個人食完20個有improved symptoms (not recovery)。
又唔知要食幾耐先好，要一直比錢買。

其實我真係好佩服發起呢個scam嘅人，好有商業頭腦。

你話我不學無術唔緊要，最起碼我有common sense ，你地班友就學太精學到全部鬼上身。

人一日要食幾多去抗抑鬱先
2-6%呢個數係冇意思